Each statin may affect vitamin D concentrations differently. Smaller, short-term studies have shown that more lipophilic statins (simvastatin and lovastatin) can cause increases in various metabolites of vitamin D, while less lipophilic statins (pravastatin) provide no improvement in vitamin D [26], [27], [28].
Is it OK to take vitamin D with statins?
Vitamin D supplement may have moderate or no effect on the dosage requirement or side effects of pravastatin, rosuvastatin and pitavastatin. Since vitamin D has mild HMG-CoA reductase activity, it will work synergistically with all statins.
What vitamins are depleted by statins?
Statins inhibit the enzyme HMG CoA reductase, and as a result, deplete a vital nutrient commonly found in fish oils. Statins have been shown to cause the depletion of Coenzyme Q10 in the body.
Can atorvastatin lower vitamin D?
Atorvastatin treatment produced a statistically significant decrease in cholesterol and triglyceride levels and an increase in vitamin D levels (41+/-19 vs 47+/-19 nmol/L, p=0.003). Vitamin D deficiency was decreased by 75% to 57% at 12 months. In conclusion, atorvastatin increases vitamin D levels.
What medications affect vitamin D absorption?
Anticonvulsants. The anticonvulsants phenobarbital and phenytoin (Dilantin, Phenytek) increase the breakdown of vitamin D and reduce calcium absorption.
24 related questions foundDoes anything interact with vitamin D?
Water pills (Thiazide diuretics) interacts with VITAMIN D
Some "water pills" increase the amount of calcium in the body. Taking large amounts of vitamin D along with some "water pills" might cause too much calcium in the body. This could cause serious side effects, including kidney problems.
Why does my vitamin D keep dropping?
A deficiency in vitamin D can result from inadequate exposure to sunlight, inefficient production in the skin, not enough vitamin D in your diet, and health conditions that can affect it including, gastrointestinal disorders, renal diseases, and liver diseases.
Does vitamin D interact with atorvastatin?
No interactions were found between atorvastatin and Vitamin D3.
What vitamins should you not take with atorvastatin?
A magnesium- and aluminum-containing antacid was reported to interfere with atorvastatin absorption. People can avoid this interaction by taking atorvastatin two hours before or after any aluminum/magnesium-containing antacids. Some magnesium supplements such as magnesium hydroxide are also antacids.
Does vitamin D affect cholesterol medication?
157 +/- 37, P < 0.005) were lower during vitamin D supplementation. The conclusion of the study is that vitamin D supplementation lowers atorvastatin and active metabolite concentrations yet has synergistic effects on cholesterol concentrations.
What foods should be avoided when taking statins?
Grapefruit juice is the only food or drink that has a direct interaction with statins. Statins do not directly interact with any food but people taking statins should moderate their intake of saturated fats to help lower their LDL cholesterol and overall risk of cardiovascular disease.
What medications should not be taken with statins?
Some drugs that may interact with statins and increase your risk of side effects include:
- Amiodarone (Cordarone, Pacerone), a medication for irregular heart rhythms.
- Gemfibrozil (Lopid), another variety of cholesterol drug.
- HIV treatments called protease inhibitors such as saquinavir (Invirase) and ritonavir (Norvir)
What do statins deplete your body of?
A highly respected chemist friend told us that the statin drugs completely deplete the body of CoQ10, and recommended blood testing of the lipid particle size before beginning any statins.
Why you should not take atorvastatin?
Statins such as atorvastatin (Lipitor) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
Is it OK to take vitamin D with Lipitor?
No interactions were found between Lipitor and Vitamin D3.
Can you drink coffee with atorvastatin?
A 2008 study on rats suggests caffeinated coffee may reduce one of the cardioprotective benefits of atorvastatin. That's because caffeine is a nonspecific adenosine receptor blocker. Adenosine receptor activation is essential for Lipitor to work. Meaning, your daily joe may make it less effective.
How much vitamin D should I be taking?
The Vitamin D Council recommends that healthy adults take 2,000 IU of vitamin D daily -- more if they get little or no sun exposure. There's evidence that people with a lot of body fat need more vitamin D than lean people.
How do you know you are vitamin D deficiency?
Symptoms of vitamin D deficiency can include muscle weakness, pain, fatigue and depression. To get enough D, look to certain foods, supplements, and carefully planned sunlight.
What is dangerously low vitamin D?
A level of 20 nanograms/milliliter to 50 ng/mL is considered adequate for healthy people. A level less than 12 ng/mL indicates vitamin D deficiency.
What are symptoms of low vitamin D?
Vitamin D deficiency can lead to a loss of bone density, which can contribute to osteoporosis and fractures (broken bones). Severe vitamin D deficiency can also lead to other diseases. In children, it can cause rickets. Rickets is a rare disease that causes the bones to become soft and bend.
Can I take vitamin D at the same time as other medications?
Yes. Certain medicines may interact with vitamin D and cause unbalanced levels in your bloodstream, so you should speak to your doctor before taking it as a supplement.
Is it OK to take vitamin D everyday?
Current guidelines say adults shouldn't take more than the equivalent of 100 micrograms a day. But vitamin D is a 'fat-soluble' vitamin, so your body can store it for months and you don't need it every day. That means you could equally safely take a supplement of 20 micrograms a day or 500 micrograms once a month.
Can you stop take statin if your cholesterol is normal?
Reducing your cholesterol levels in this way can help reduce your overall risk of a heart attack, stroke, or blocked arteries while allowing you to take one less medication. But don't stop taking your statin because you think your cholesterol levels are automatically better because of your lifestyle changes.
At what age should you stop statins?
Adults age 75 and older may not need statins.
Many older adults have high cholesterol. Their doctors usually prescribe statins to prevent heart disease. But for older people, there is no clear evidence that high cholesterol leads to heart disease or death.
Do statins clear the arteries of plaque?
Statins help lower low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, in the blood. They draw cholesterol out of plaque and stabilize plaque, Blaha says.